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Usage of cimetidine with oral metronidazole may possibly prolong the half-everyday living and decrease plasma clearance of metronidazole.
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Regarded or Beforehand unrecognized vaginal candidiasis could current more distinguished signs or symptoms in the course of therapy with metronidazole vaginal gel. Somewhere around six-ten% of people treated with METROGEL-VAGINAL produced symptomatic Candida vaginitis in the course of or promptly after therapy.
Offered information haven't set up an association in between metronidazole use during pregnancy and big delivery defects, miscarriage or other adverse maternal or fetal outcomes. No fetotoxicity was observed immediately after oral administration of metronidazole in Expecting rats or mice.
Convulsive seizures and peripheral neuropathy, the latter characterised primarily by numbness or paresthesia of an extremity, are already described in people addressed with oral or intravenous metronidazole.
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